Only if your philosophy relies on you defining yourself with all of the parameters of the human condition, rather than with just a strict subset of that.
The logical result of the desire to transcend, combined with the loss of guiding constraints is something like this:
https://transforum.fractalfuture.net/t/epistemological-consequentialism/791
Constant state of existential angst? Been there, done that. I built it into the basis of my philosophy. Standing on it works better than I had even expected to make sense.
An important question for you, @AlonzoTG: Is human nature sustainable?